Bill & Melinda Gates Foundation

VecNet is funded by the Bill & Melinda Gates Foundation.

 

 

As part of Intellectual Ventures' Global Good initiative, the Institute for Disease Modeling is committed to improving and saving lives in developing countries. IDM focuses on creating powerful and innovative disease modeling and data analysis tools to help researchers and policy makers understand diseases and evaluate the efficacy of eradication and control alternatives. The Institute for Disease Modeling develops detailed, geographically-specific, and mechanistic stochastic models of disease transmission simulations through the use of extensive and complex software modeling. IDM will help enable broad accessibility of modeling and quantitative analysis tools to achieve acceptance and utilization of data-driven computer models as decision making tools in the eradication and control of infectious diseases.

 

 

James Cook University is dedicated to creating a brighter future for life in the tropics world-wide from campuses in Townsville, Cairns and Singapore, through graduates and discoveries that make a difference. The University conducts nationally significant and internationally recognised research in areas such as marine sciences, biodiversity, tropical ecology and environments, global warming, tourism, and tropical medicine and public health care in under-served populations.

James Cook University has particular strengths in research in vector borne diseases such as malaria, lymphatic filariasis and dengue and is home to the VecNet secretariat under the direction of Professor Tom Burkot and Dr Michelle Barker, the VecNet Orchestrator and Program Director, respectively.

 

 

R. Farlow Consulting, LLC

R. Farlow Consulting, LLC provides professional consulting expertise to public and private entities in research and development, technical support, product stewardship and implementation of projects that improve the quality of life. Dr. Robert Farlow leads the development of the Product Impact Evaluator, (PIE), which enables product developers and researchers to estimate the impact of candidate tools on malaria transmission. The web based interactive tool will provide an end-user the ability to estimate the impact of new candidate tools on vector control and malaria transmission, develop and refine the Target Product Profiles needed to achieve a particular level of impact, explore implementation strategies for new products and conduct in-silico experiments to evaluate the impact of varying product parameters.

 

 

 

Within Swiss Tropical and Public Health Institute (Swiss TPH), the department of Epidemiology and Public Health (EPH) is organized in 23 Research Groups that are administratively and strategically assembled in eight Research Units. Research groups of several units within EPH are involved in malaria research:

  • Malaria Interventions Group: The development of new health interventions, especially in the field of malaria, is one of the long-standing and most successful traditions at Swiss TPH. The Health Interventions Unit works on all aspects of applied research against malaria, from testing new vaccines to implementing proven control tools at national level. The generation of new evidence on current vector control measures is continuously pursued, in synergy with expert advisory activities at global level. An important area of activity is the introduction of better diagnostic approaches and improving access to quality fever case management. Finally, our unit is involved in applied control activities, such as the national Insecticide-Treated Net (ITN) programme in Tanzania.

    For more information about this group, please click here.

  • Malaria Vaccines Group: Swiss TPH works with GlaxoSmithKline (GSK) Biologicals to produce and test malaria vaccines. A recently completed Phase 3 trial undertaken at the IHI’s Bagamoyo branch, as well as in 10 other African centres and including 16,000 infants and small children, demonstrated a 56% protection rate against malaria episodes and a 34% reduction in severe malaria incidence. The group is also involved in a number of other trials of vaccine candidates, as well as in the immunological study of the vaccine’s responses.

    For more information about this group, please click here.

  • Dynamical Modeling Group: Activities relevant to VecNet are mostly performed in the Health Systems Research and Dynamical Modelling (HSRDM) unit. This research unit focuses on understanding infection dynamics, in the context of real-world disease and health systems, using a range of computational tools from statistics, mathematics and computer science. The group’s main focus has been on Plasmodium falciparummalaria, and on developing a general platform for comparing, fitting and evaluating micro-simulation models of malaria dynamics. The platform is used to quantitatively predict the effects of different interventions and integrated control programmes. The group is also actively involved in designing and analyzing field studies, and is diversifying the modelling activities to consider a wider range of vector-borne diseases, bacterial infections and system interventions.

    For more information about this group, please click here.

 

 

ND mark 200

The University of Notre Dame's major malaria research activity includes directing the Malaria Transmission Consortium, a group of scientists at multiple research institutions who work on developing more effective ways to measure malaria transmission and use those measures to better assess the effectiveness of malaria control methods that target mosquito vectors.

Agent-based simulation models of the African malaria vector, Anopheles gambiae, is also being developed at Notre Dame. These models include both non-spatial and spatial aspects of the vector's lifecycle and malaria transmission.

Notre Dame also hosts a web portal called the Garki Information Resource, which is an attempt to make data publicly available from the Garki Project. The Garki Project is a study carried out in the Garki District of northern Nigeria in 1969-76 by a joint WHO and Nigerian Government research team. This portal is maintained by the Center for Research Computing at Notre Dame.

 

 

 

The Malaria Atlas Project (MAP), based at the University of Oxford and led by Dr. Simon Hay, contributes expertise on the spatial distribution of vector species to VecNet. MAP’s vector work is led by Dr. Marianne Sinka who has assembled a database of occurrence data for the 41 dominant vector species or species complexes (DVS) of malaria. Additionally, the MAP team is collating bionomics and behavioural information for each of the DVS and generating quantified and spatially linked values for specific behaviours relevant to control of the DVS. The Malaria Atlas Project is part of the Spatial Ecology and Epidemiology Group within the University’s Department of Zoology. The University of Oxford supports other large-scale malaria research projects including MalariaGEN and WWARN.